Just take this medicine only as directed by your doctor. Never consider far more of it, usually do not get it much more usually, and don't take it for a longer time than your health care provider ordered. If too much of the medication is taken for a long period, it may well turn out to be habit-forming and lead to psychological or Actual physical dependence.
Administration of codeine can be accompanied by histamine launch and should be utilised with warning in atopic children.
The mixture of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric clients under 6 many years of age, simply because The mix may well bring about fatal respiratory despair With this age populace (see WARNINGS – Box Warning and Use In Pediatric Patients).
Promethazine could lessen seizure threshold. It ought to be applied with warning in folks with seizure Problems or in folks who're making use of concomitant drugs, such as narcotics or nearby anesthetics, which may also have an effect on seizure threshold.
Sedating medicines may possibly induce confusion and over-sedation inside the elderly; elderly individuals generally needs to be commenced on small doses of promethazine with codeine syrup and noticed intently.
Promethazine with Codeine Syrup, a clear purple syrup with odor of grape menthol, is made up of promethazine hydrochloride six.
This drugs might be taken with foodstuff or simply a glass of drinking water or milk to lessen belly irritation if essential.
Before working with here this medication, Females of childbearing age ought to converse with their health practitioner(s) regarding the risks and Added benefits. Inform your health care provider Should you be Expecting or Feel you may well be pregnant. Through pregnancy, this medication isn't advisable. It may well marginally enhance the danger of start defects if made use of through the initially two months of pregnancy. Also, utilizing it for years or in high doses near the anticipated shipping day may perhaps hurt the unborn baby.
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Making use of this drugs with any of the subsequent medicines could bring about an increased threat of selected Unwanted effects, but applying each medicines often is the best remedy in your case. If both of those medicines are prescribed with each other, your doctor could alter the dose or how frequently you utilize a single or both equally of your medicines.
Promethazine is effectively absorbed with the gastrointestinal tract. Scientific consequences are clear within twenty minutes after oral administration and generally final 4 to six hrs, Despite the fact that They might persist providing twelve hrs.
Individuals must be cautioned to stay away from prolonged sun exposure and report any involuntary muscle movement.
Ensure that you know how you react to this medication prior to deciding to travel, use machines, or do anything that would be dangerous if you are not inform .
The opioid antagonists, naloxone and nalmefene, are distinct antidotes for respiratory melancholy ensuing from opioid overdose. For clinically significant respiratory or circulatory despair secondary to codeine overdose, administer an opioid antagonist. An antagonist shouldn't be administered inside the absence of clinically substantial respiratory depression. As the period of opioid reversal is anticipated for being under the duration of action of codeine in Promethazine with Codeine Oral Solution, carefully watch the client until eventually spontaneous respiration is reliably reestablished.